Effects of phlorotannin and polysaccharide fractions of brown seaweed Silvetia compressa on human gut microbiota composition using an in vitro colonic model

Few studies had demonstrated the interaction of phlorotannins and polysaccharides from algae on microbial diversity growth probiotic bacteria early stages colonic fermentation. Silvetia compresssa hydroethanolic extract rich in its isolated fraction enabled proliferation Bifidobacterium Lactobacillus increased total short-chain fatty acids synthesis compared to a negative control. Eckstolonol, dieckol acacetin derivative were depleted after eight hours vitro After 48 h fermentation, showed high levels acetic (104.82 µmol g?1 wet feces) propionic (78.58 feces), as well an increase (log10 6.77 CFU 4.25 growth. These results no significant difference with inulin (p > 0.05), suggesting potential improve human gut microbiota.